Cutaneous manifestations of Churg-Strauss syndrome: A clinicopathologic correlation
Identifieur interne : 002950 ( Main/Exploration ); précédent : 002949; suivant : 002951Cutaneous manifestations of Churg-Strauss syndrome: A clinicopathologic correlation
Auteurs : Mark D. P. Davis ; Mazen S. Daoud ; Marian T. Mcevoy ; W. P. Daniel SuSource :
- Journal of the American Academy of Dermatology [ 0190-9622 ] ; 1997.
English descriptors
- Teeft :
- Acad dermatol, Allergic, Allergic granulomatosis, American academy, Asthma, Biopsy specimens, Churg, Common findings, Cutaneous, Cutaneous findings, Cutaneous lesions, Cutaneous manifestations, Dermatol, Dermatology, Eosinophilia, Extravascular, Extravascular necrotizing granuloma, Fibrinoid necrosis, Granuloma, Granulomatosis, Lesion, Leukocytoclastic, Leukocytoclastic vasculitis, Lower extremities, Necrotizing, Nodosa, Nuclear dust, Periarteritis nodosa, Skin lesions, Syndrome, Systemic, Systemic disease, Systemic vasculitis, Vasculitis, Winkelmann.
Abstract
Abstract: Background: Allergic granulomatosis of Churg-Strauss (Churg-Strauss syndrome) is a distinct clinical disease of multisystem vasculitis. Objective: We characterize the clinical and histologic features of cutaneous findings in Churg-Strauss syndrome. Methods: All patients with Churg-Strauss syndrome seen between 1976 and 1995 were retrospectively reviewed. Results: Ninety patients with the diagnosis of Churg-Strauss syndrome were identified; 36 (40%) had cutaneous findings. Five patients (6%) had skin lesions as the initial manifestation. The most frequent cutaneous findings were purpura and petechiae on the lower extremities and cutaneous nodules and papules on the elbows. In 37 biopsy specimens from 29 patients, the most common findings were extravascular necrotizing granuloma (15 specimens) and leukocytoclastic vasculitis (16 specimens). Conclusion: Cutaneous lesions in Churg-Strauss syndrome are common. Their characteristic clinical and histologic pattern may help establish the diagnosis. (J Am Acad Dermatol 1997;37:199-203.)
Url:
DOI: 10.1016/S0190-9622(97)80125-9
Affiliations:
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P." last="Davis">Mark D. P. Davis</name><affiliation><wicri:noCountry code="subField">Rochester</wicri:noCountry></affiliation></author><author><name sortKey="Daoud, Mazen S" sort="Daoud, Mazen S" uniqKey="Daoud M" first="Mazen S." last="Daoud">Mazen S. Daoud</name><affiliation><wicri:noCountry code="subField">Rochester</wicri:noCountry></affiliation></author><author><name sortKey="Mcevoy, Marian T" sort="Mcevoy, Marian T" uniqKey="Mcevoy M" first="Marian T." last="Mcevoy">Marian T. Mcevoy</name><affiliation><wicri:noCountry code="subField">Rochester</wicri:noCountry></affiliation></author><author><name sortKey="Daniel Su, W P" sort="Daniel Su, W P" uniqKey="Daniel Su W" first="W. P." last="Daniel Su">W. P. Daniel Su</name><affiliation><wicri:noCountry code="subField">Rochester</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of the American Academy of Dermatology</title><title level="j" type="abbrev">YMJD</title><idno type="ISSN">0190-9622</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1997">1997</date><biblScope unit="volume">37</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="supplement">P1</biblScope><biblScope unit="page" from="199">199</biblScope><biblScope unit="page" to="203">203</biblScope></imprint><idno type="ISSN">0190-9622</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0190-9622</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acad dermatol</term><term>Allergic</term><term>Allergic granulomatosis</term><term>American academy</term><term>Asthma</term><term>Biopsy specimens</term><term>Churg</term><term>Common findings</term><term>Cutaneous</term><term>Cutaneous findings</term><term>Cutaneous lesions</term><term>Cutaneous manifestations</term><term>Dermatol</term><term>Dermatology</term><term>Eosinophilia</term><term>Extravascular</term><term>Extravascular necrotizing granuloma</term><term>Fibrinoid necrosis</term><term>Granuloma</term><term>Granulomatosis</term><term>Lesion</term><term>Leukocytoclastic</term><term>Leukocytoclastic vasculitis</term><term>Lower extremities</term><term>Necrotizing</term><term>Nodosa</term><term>Nuclear dust</term><term>Periarteritis nodosa</term><term>Skin lesions</term><term>Syndrome</term><term>Systemic</term><term>Systemic disease</term><term>Systemic vasculitis</term><term>Vasculitis</term><term>Winkelmann</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Background: Allergic granulomatosis of Churg-Strauss (Churg-Strauss syndrome) is a distinct clinical disease of multisystem vasculitis. Objective: We characterize the clinical and histologic features of cutaneous findings in Churg-Strauss syndrome. Methods: All patients with Churg-Strauss syndrome seen between 1976 and 1995 were retrospectively reviewed. Results: Ninety patients with the diagnosis of Churg-Strauss syndrome were identified; 36 (40%) had cutaneous findings. Five patients (6%) had skin lesions as the initial manifestation. The most frequent cutaneous findings were purpura and petechiae on the lower extremities and cutaneous nodules and papules on the elbows. In 37 biopsy specimens from 29 patients, the most common findings were extravascular necrotizing granuloma (15 specimens) and leukocytoclastic vasculitis (16 specimens). Conclusion: Cutaneous lesions in Churg-Strauss syndrome are common. Their characteristic clinical and histologic pattern may help establish the diagnosis. (J Am Acad Dermatol 1997;37:199-203.)</div></front></TEI><affiliations><list></list><tree><noCountry><name sortKey="Daniel Su, W P" sort="Daniel Su, W P" uniqKey="Daniel Su W" first="W. P." last="Daniel Su">W. P. Daniel Su</name><name sortKey="Daoud, Mazen S" sort="Daoud, Mazen S" uniqKey="Daoud M" first="Mazen S." last="Daoud">Mazen S. Daoud</name><name sortKey="Davis, Mark D P" sort="Davis, Mark D P" uniqKey="Davis M" first="Mark D. P." last="Davis">Mark D. P. Davis</name><name sortKey="Mcevoy, Marian T" sort="Mcevoy, Marian T" uniqKey="Mcevoy M" first="Marian T." last="Mcevoy">Marian T. Mcevoy</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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